Conditioned taste aversion, drugs of abuse and palatability
نویسندگان
چکیده
منابع مشابه
Conditioned taste aversion and drugs of abuse: history and interpretation.
Conditioned taste aversion (CTA) learning describes a phenomenon wherein an animal learns to avoid consumption of a particular taste or food following its pairing with an aversive stimulus. Although initially demonstrated with radiation and classical emetics, CTAs have also been shown with drugs of abuse. The ability of rewarding drugs to support CTA learning was described as paradoxical by man...
متن کاملMagnetic field conditioned taste aversion in rats.
Conditioned taste aversion is a common classic conditioning procedure used to identify noxious stimuli. When a rat is given a taste solution, the conditioned stimulus (CS), followed by an unpleasant experience, the unconditioned stimulus (US), the rat will avoid consumption of the CS in future presentations. These experiments use the taste aversion procedure to examine the effect of exposure to...
متن کاملConditioned taste aversion learning: implications for animal models of drug abuse.
Drugs of abuse are typically discussed in terms of their rewarding effects and how these effects mediate drug taking. However, these drugs produce aversive effects that could have an important role in the overall acceptability of a drug and its likelihood of being self-administered. Rewarding and aversive effects, then, could be interpreted as separate behavioral effects, with the balance of th...
متن کاملNonreinforced flavor exposure attenuates the effects of conditioned taste aversion on both flavor consumption and cue palatability.
Nonreinforced exposure to a cue tends to attenuate subsequent conditioning with that cue-an effect referred to as latent inhibition (LI). In the two experiments reported here, we examined LI effects in the context of conditioned taste aversion by examining both the amount of consumption and the microstructure of the consummatory behavior (in terms of the mean size of lick clusters). The latter ...
متن کاملConditioned Taste Aversion Learning in Adolescent and Adult Rats
Pharmacology and Cancer Biology at the Duke University Medical Center in Durham, NC. In 2004, Dr. Schramm-Sapyta and her colleagues at Vanderbilt assessed the rewarding effects of cocaine in adolescent and adult rats and noted no distinct differences in the acquisition of cocaine-induced place preferences between the two groups. Given her focus on the balance of the rewarding and aversive effec...
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ژورنال
عنوان ژورنال: Neuroscience & Biobehavioral Reviews
سال: 2014
ISSN: 0149-7634
DOI: 10.1016/j.neubiorev.2014.05.001